Project

Detailed studie of the role of type-I IFN in TNF-induced and TNF-mediated pathologies

Code
178WE0811
Duration
01 October 2010 → 05 January 2016
Funding
Regional and community funding: IWT/VLAIO
Research disciplines
  • Medical and health sciences
    • Immunology
    • Immunology
    • Microbiology
    • Immunology
Keywords
cytokines inflammation
 
Project description

The induction of inflammation by TNF forms the basis of countless inflammatory diseases. In the past, we have shown that part of the activity of TNF is mediated by interferons (IFNs). In this project, we want to investigate the mechanism by which IFNs add to the TNF-induced inflammation.