Code
01SC0518
Duration
01 October 2018 → 30 September 2022
Funding
Regional and community funding: Special Research Fund
Promotor
Fellow
Research disciplines
-
Natural sciences
- Animal biology
- Microbiology
- Systems biology
-
Medical and health sciences
- Immunology
- Laboratory medicine
- Microbiology
- Immunology
- Laboratory medicine
- Immunology
- Laboratory medicine
- Microbiology
-
Agricultural and food sciences
- Veterinary medicine
- Other veterinary sciences
- Other agricultural, veterinary and food sciences
Keywords
Alphaherpesvirus
pseudorabies
type III interferon
interferon l
epithelial cells
Project description
Many alphaherpesviruses invade their host via mucosae of the upper respiratory tract. Interferons are
the most powerful antiviral cytokines, and prevent alphaherpesviruses from causing aggravated, life-
threatening disease. The project will investigate the interaction of alphaherpesviruses with type III interferons in respiratory epithelia, since increasing evidence indicates that these most recently
described interferons are critical in the mucosal antiviral defence.