Research Explorer

Project

Furan-based Artificial DNA Anchoring Systems

Acronym
3PL001116
Code
3PL01116W
Duration
01 March 2017 → 29 February 2020
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Macromolecular and materials chemistry
    • Organic chemistry
  • Engineering and technology
    • Biomaterials engineering
    • Biological system engineering
    • Biomaterials engineering
    • Biomechanical engineering
    • Other (bio)medical engineering
    • Environmental engineering and biotechnology
    • Industrial biotechnology
    • Other biotechnology, bio-engineering and biosystem engineering
Keywords
DNA crosslink Peptide nucleic acids furan
 
Project description

The project will be focussed on the realization of peptide nucleic acid (PNA) derivatives containing a furan mojety as a pro-reactive group for DNA-crosslinking.
During the project different modifications of the standard PNA backbone and/or nucleobases will be taken into account.
The final aim of the project is the realization of a diagnostic platform, based on this systems.