Project

Unravelling the causes of failed fertilization after intracytoplasmic sperm injection (ICSI)

Duration
01 January 2015 → 31 December 2020
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Genetics
  • Medical and health sciences
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
    • Molecular and cell biology
    • Morphological sciences
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
    • Molecular and cell biology
    • Morphological sciences
    • Nursing
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
    • Molecular and cell biology
    • Morphological sciences
Keywords
failed fertilization oocyte activation ICSI
 
Project description

Failed fertilization after ICSI occurs in some couples, mostly due to an oocyte activation deficiency. Both the sperm and the oocyte play an important role in this oocyte activation mechanism. We want to explore new diagnostic tests and causes in this deficiency of sperm or oocytes, which might lead to new treatment options to overcome failed fertilization.