Research Explorer

Project

The rational design and validation of a Salmonella Typhimurium vaccin by deletion of virulence genes for use in pigs
Code
17808908
Duration
01 February 2008 → 31 January 2010
Funding
Regional and community funding: IWT/VLAIO
Research disciplines
  • Natural sciences
    • Animal biology
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Laboratory medicine
    • Microbiology
    • Laboratory medicine
    • Laboratory medicine
    • Microbiology
  • Agricultural and food sciences
    • Veterinary medicine
    • Other veterinary sciences
    • Other agricultural and food sciences
Keywords
salmonella pig vaccine
 
Project description
 

In this project, extensively characterized, live, attenuated vaccinstrains of Salmonella Typhimurium are made. These strains should evoke a good protection against a Salmonella infection in pigs and be attenuated in humans, animals and the environment. In addition, the pigs vaccinated with these strains, should be serologically distinguishable from pigs infected with field strains of Salmonella in the current national Salmonella pig control programme.