Research Explorer

Project

Tunneling nanotubes induced by the US3 protein of alphaherpesviruses
Code
3G019617N
Duration
01 January 2017 → 31 December 2020
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Cellular interactions and extracellular matrix
  • Medical and health sciences
    • Virology
Keywords
Herpes pseudorabies US3 tunneling nanotubes intercellular communication
 
Project description

Our research team has discovered that alphaherpesviruses can spread from one cell to another via the induction of cell projections, so-called tunneling nanotubes (TNTs). These TNTs are induced by the viral kinase US3. The aim of the project is to unravel the mechanism of US3-induced TNT formation and to investigate which type of information is spread via the TNTs.