Research Explorer

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Project

Tunneling nanotubes induced by the US3 protein of alphaherpesviruses

Outputs and Outcomes

Code

3G019617N

Duration

01 January 2017 → 31 December 2020

Funding

Research Foundation - Flanders (FWO)

Promotor

Herman Favoreel

Research disciplines

Natural sciences
- Cellular interactions and extracellular matrix
Medical and health sciences
- Virology

Keywords

Herpes pseudorabies US3 tunneling nanotubes intercellular communication

Project description

Our research team has discovered that alphaherpesviruses can spread from one cell to another via the induction of cell projections, so-called tunneling nanotubes (TNTs). These TNTs are induced by the viral kinase US3. The aim of the project is to unravel the mechanism of US3-induced TNT formation and to investigate which type of information is spread via the TNTs.

English

Dutch

English

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