Project

Electron nuclear double resonance (ENDOR) strategy for studying radiation damage to DNA

Code
01D25613
Looptijd
01-10-2013 → 30-09-2017
Financiering
Regional and community funding: Special Research Fund
Onderzoeksdisciplines
  • Natural sciences
    • Electronic (transport) properties
    • Optical properties and interactions with radiation
    • Materials physics not elsewhere classified
Trefwoorden
ioniserende straling DNA suiker radicalen elektronen magnetische resonantie
 
Projectomschrijving

This research focuses on the identification of radicals, produced in DNA via ionizing radiation, using electron nuclear double resonance (ENDOR) as main spectroscopic tool. No large single crystals can be made from DNA, as a result experiments have to be performed on powders and frozen soluitions. The ENDOR methodology for such disordered systems will first be developed via a case study on sugars.