Research Explorer

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Project

Interaction of Escherichia coli fimbriae with carbohydrate receptors of porcine enterocytes and the fimbriae-specific mucosal immune response

Outputs and Outcomes

Code

3G038907

Duration

01 January 2007 → 30 December 2012

Funding

Research Foundation - Flanders (FWO)

Promotor

Eric Cox

Research disciplines

Medical and health sciences
- Immunology
- Immunology
- Microbiology
- Immunology

Keywords

fimbrial receptors pathogenic Escherichia coli mucosal immunity

Project description

Piglets are very susceptible to infection with pathogenic EScherichia coli strains that adhere with their fimbriae to small intestinal enterocytes, colonise the intestine and cause diarrhoea by toxin secretion. The aim of this project is to identify fimbrial receptors and to analyse the interaction of these pathogens with the mucosal immune system of the host.

English

Dutch

English

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