Project

Interaction of Escherichia coli fimbriae with carbohydrate receptors of porcine enterocytes and the fimbriae-specific mucosal immune response

Code
3G038907
Duration
01 January 2007 → 30 December 2012
Funding
Research Foundation - Flanders (FWO)
Promotor
Research disciplines
  • Medical and health sciences
    • Immunology
    • Immunology
    • Microbiology
    • Immunology
Keywords
fimbrial receptors pathogenic Escherichia coli mucosal immunity
 
Project description

Piglets are very susceptible to infection with pathogenic EScherichia coli strains that adhere with their fimbriae to small intestinal enterocytes, colonise the intestine and cause diarrhoea by toxin secretion. The aim of this project is to identify fimbrial receptors and to analyse the interaction of these pathogens with the mucosal immune system of the host.