Understanding the prevalence of acquired antimicrobial resistance of zoonotic and indicator bacteria in pigs and poultry and describing the use of antimicrobial agents in these sectors. Further on, the effect of a reduced prophylactic use of antimicrobial agents on antimicrobial resistance of zoonotic and indicator bacteria will be studied on middle long term. The aim is to show a possibility of a reduced antimicrobial agent use due to accompanying measurements and to show that a reduced use of antimicrobials can lead to a decreased antimicrobial resistance level of zoonotic and indicator bacteria on middle long term.