Acronym
ChargeShift
Code
F2021/IOF-ConcepTT/067
Duration
15 July 2021 → 14 July 2022
Funding
Regional and community funding: Industrial Research Fund
Promotor
Research disciplines
-
Medical and health sciences
- Biopharmaceutics
- Pharmaceutical technology
Keywords
lipid nanoparticles
RNA
vaccines
nucleic acid
Ionizable lipids
Project description
We have recently filed IP on a novel library of ionizable lipids for lipid nanoparticle (LNP) mediated delivery of nucleic acid based drugs. ConcepTT funding will be used to chemically synthesize the library of ionizable lipids, characterize mRNA LNP formulations and test their biological activity in vitro and in vivo.