Project

Drug load microbubbles for ultrasound targeted delivery in breast cancer therapy: from the model of the canine mammary gland tumors

Duration
01 October 2011 → 30 September 2014
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Animal biology
  • Medical and health sciences
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
    • Morphological sciences
    • Oncology
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
    • Morphological sciences
    • Oncology
    • Nursing
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
    • Morphological sciences
    • Oncology
  • Agricultural and food sciences
    • Veterinary medicine
    • Other veterinary sciences
    • Other agricultural, veterinary and food sciences
Keywords
oncology breast cancer canine model contrast-enhanced ultrasound
 
Project description

The canine mammary gland tumor offers an interesting animal model for breast cancer in women. Contrast-enhanced ultrasonography (CEUS) may increase the efficacy of chemotherapeutics as drugs (doxorubicin liposomes) can be incorporated into the microbubble's lipid shell. With this innovative project we hope to demonstrate the diagnostic and improved therapeutic efficacy of CEUS in canine mammary gland tumors and to show the canine model's.