Project

Study of crosstalk between neurotransmitter and inflammatory signals in the context of neuro-inflammation

Duration
01 October 2008 → 01 October 2010
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Biochemistry and metabolism
  • Social sciences
    • Biological and physiological psychology
    • Cognitive science and intelligent systems
    • Developmental psychology and ageing
  • Medical and health sciences
    • Immunology
    • Medical biochemistry and metabolism
    • Neurosciences
    • Immunology
    • Medical biochemistry and metabolism
    • Neurosciences
    • Immunology
    • Medical biochemistry and metabolism
    • Neurosciences
Keywords
Alzheimer neurotransmitters NFkB neuro-inflammation
 
Project description

Recently, a link between neuro-inflammation and the etiology of neurodegenerative affections, such as Alzheimer's disease, has been demonstrated. In this study, we will investigate how neurotransmitters can modulate the function of the pro-inflammatory transcription factor NFkB. We will perform in vitro assays using astrocyte cell models as well as in vivo experiments with rodent models.