Project

Differential gene expression of intestinal dendritic cells after (in vivo) interaction with soluble immunogenic or tolerogeneic antigens

Duration
01 January 2007 → 31 December 2009
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Medical and health sciences
    • Immunology
    • Immunology
    • Microbiology
    • Immunology
Keywords
dendritic cells mucosal immunity intenstine
 
Project description

Dendritic cells will be isolated from the small intestine of weaned piglets after stimulation with soluble immunogenic and tolerogeneic antigens. The influence of these antigens on the maturation of intestinal dendritic cells will be analysed by flowcytometric analysis of co-stimulatory molecules and analysis of cytokine/chemokine gene expression.