Research Explorer

Project

Protection against influenza A virus infection and modulation of antigen presentation by matrix protein 2-specific antibodies.
Code
3G043515
Looptijd
01-01-2015 → 31-12-2020
Financiering
Research Foundation - Flanders (FWO)
Onderzoeksdisciplines
  • Medical and health sciences
    • Infectious diseases
    • Virology
    • Pathophysiology
    • Vaccinology
    • Vaccines
Trefwoorden
antigenpresentatie M2e immuniteit influenza
 
Projectomschrijving

Matrix protein 2 ectodomain (M2e) specific antibodies protect against disease caused by influenza A viruses. M2e-based immune protection is infection permissive, meaning that viral replication is blunted but not prevented. In this project, we will study if and how M2e-based immune protection modulates the adaptive immune response following challenge.