Research Explorer

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Project

Unraveling the in vivo role of RIPK1: Physiological and pathological consequences of kinase-dependent and kinase-independent functions

Outputs and Outcomes

Publications

RIPK1 ablation in T cells results in spontaneous enteropathy and TNF-driven villus atrophy

Jelle HuysentruytWolf SteelsMario Ruiz PérezBruno VerstraetenTatyana DivertKayleigh FliesKelly LemeireNozomi TakahashiElke De BruynMarie JoossensAndrew BrownBart LambrechtWim DeclercqTom Vanden BergheJonathan MaelfaitPeter VandenabeelePeter Tougaard et al.

A1 Journal Article in EMBO REPORTS

Ferroptosis contributes to multiple sclerosis and its pharmacological targeting suppresses experimental disease progression

Emily Van SanAngela DebruyneGeraldine VeeckmansYulia Y. Y. TyurinaVladimir A. A. TyurinHao ZhengSze Men ChoiKoen AugustynsGeert van LooBernhard MichalkeVivek VenkataramaniShinya ToyokuniHuelya BayirPeter VandenabeeleBehrouz HassanniaTom Vanden Berghe et al.

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD

Hannelore Van EeckhoutteChantal DonovanRichard Y. KimThomas M. ConlonMeshal AnsariHaroon KhanRanjith JayaramanNicole G. HansbroYves DondelingerTom DelangheAllison M. BealBrad GeddesJohn BertinTom Vanden BergheJoyceline De VolderTania MaesPeter VandenabeeleBart M. VanaudenaerdeDieter DeforceSonja SkevinFilip Van NieuwerburghFien VerhammeGuy JoosSobia IdreesHerbert B. SchillerAli Önder YildirimAlen FaizMathieu BertrandGuy BrussellePhilip M. HansbroKen Bracke et al.

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Association of cell death markers with tumor immune cell infiltrates after chemo-radiation in cervical cancer

Teodora-Eugenia OlteanLien LippensKelly LemeireCaroline De TenderMarnik VuylstekeHannelore DenysKatrien VandecasteelePeter VandenabeeleSandy Adjemian Catani

A1 Journal Article in FRONTIERS IN ONCOLOGY

Reduced protection of RIPK3-deficient mice against influenza by matrix protein 2 ectodomain targeted active and passive vaccination strategies

Teodora-Eugenia OlteanLorena IbanezTatyana DivertTine YsenbaertHannelore Van EeckhoutteVera GoossensMichael SchotsaertKen BrackeBert SchepensJonathan MaelfaitNozomi TakahashiXavier SaelensPeter Vandenabeele et al.

A1 Journal Article in CELL DEATH & DISEASE

Viral manipulation of host cell necroptosis and pyroptosis

Simon VerdonckJosephine NemegeerPeter VandenabeeleJonathan Maelfait

A1 Journal Article in TRENDS IN MICROBIOLOGY

Executioner caspases 3 and 7 are dispensable for intestinal epithelium turnover and homeostasis at steady state

Farzaneh GhazaviJelle HuysentruytJordy De ConinckStephanie KourulaSofie MartensBehrouz HassanniaTim WartewigTatyana DivertRia RoelandtBastian PopperAndreas HiergeistPeter TougaardTom Vanden BergheMarie JoossensGeert BerxNozomi TakahashiAdam WahidaPeter Vandenabeele et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasma membrane perforation by GSDME during apoptosis-driven secondary necrosis

Elke De SchutterJana RamonBenjamin PfeutyCaroline De TenderStephan StremerschKoen RaemdonckKen Op de BeeckWim DeclercqFranck RiquetKevin BraeckmansPeter Vandenabeele et al.

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES