Code
3E010009
Duration
01 October 2009 → 30 November 2011
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Promotor
Fellow
Research disciplines
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Natural sciences
- Organic chemistry
- Other chemical sciences
-
Medical and health sciences
- Laboratory medicine
- Medical systems biology
- Laboratory medicine
- Medical systems biology
- Medicinal chemistry
- Laboratory medicine
- Medical systems biology
-
Agricultural and food sciences
- Agricultural plant production
Keywords
pyranonaphthoquinones
2-azaanthraquinones
antibiotics
benzophenantridinediones
Project description
Quinones are natural products and display a variety of biological activities, amongst which antibiotic and antitumour activity, which makes them an important class of compounds for the development of new drugs. Furthermore, the development of bacterial multiresistance in case of antibiotics represents a real problem, which necessitates continued research to new active compounds. In this respect, the current research proposal aims to develop efficient syntheses of potentially bioactive pyranonaphthoquinones, benzophenantridinediones and 2-azaanthraquinones.