Code
365H5608
Duration
01 October 2008 → 31 March 2010
Funding
Funding by bilateral agreement (private and foundations)
Promotor
Research disciplines
-
Natural sciences
- Biochemistry and metabolism
- Systems biology
-
Medical and health sciences
- Medical biochemistry and metabolism
- Morphological sciences
- Oncology
- Medical biochemistry and metabolism
- Morphological sciences
- Oncology
- Medical biochemistry and metabolism
- Morphological sciences
- Oncology
-
Engineering and technology
- Catalysis and reacting systems engineering
- Chemical product design and formulation
- General chemical and biochemical engineering
- Process engineering
- Separation and membrane technologies
- Transport phenomena
- Other (bio)chemical engineering
Keywords
nanobody
gelsolin
VHH
Project description
Lama single domain antibodies raised against gelsolin will be used to neutralize the activity of this protein, primarily in cancer cells. By investigating where in gelsolin these nanobodies bind we can better understand how this protein contributes to malignant cell behavior.