Project

Mutations in DNA double strand break repairgenes as biomarkers for breast cancer predisposition

Duration
01 January 2008 → 31 December 2010
Funding
Research Foundation - Flanders (FWO)
Promotor
Research disciplines
  • Natural sciences
    • Microbiology
  • Medical and health sciences
    • Laboratory medicine
    • Medical systems biology
    • Microbiology
    • Laboratory medicine
    • Medical systems biology
    • Microbiology
    • Molecular and cell biology
    • Public health care
    • Public health sciences
    • Public health services
    • Laboratory medicine
    • Medical systems biology
    • Microbiology
    • Molecular and cell biology
  • Agricultural and food sciences
    • Veterinary medicine
Keywords
mutation breast cancer SNP chromosomal radiosensitivity DNA repair genes biomarker RNAinterference
 
Project description

The aim of this project is: - identification of mutations in DNA double strand break repair genes, that result in a radiosensitive phenotype and are linked to breast cancer predisposition - the development of useful predictive biomarkers to evaluate the individual breast cancer risk in a healthy female population.