Identification of T cell antigenic peptides in MHC complexes on Chronic Lymphocytic Leukemia B cells

01 January 2008 → 30 December 2013
Research Foundation - Flanders (FWO)
Research disciplines
  • Medical and health sciences
    • Biomarker discovery and evaluation
    • Drug discovery and development
    • Medicinal products
    • Pharmaceutics
    • Pharmacognosy and phytochemistry
    • Pharmacology
    • Pharmacotherapy
    • Toxicology and toxinology
    • Other pharmaceutical sciences
mass spectrometry peptides CLL
Project description

Peptides will be isolated from MHC complexes present on CLL B cells. These peptides will be investigated to analyse their potential to elucidate a T cell response. The peptides able to activate specific T cells will be identified using mass spectrometric analytical techniques.