Research Explorer

Project

Patient-tailored antibiotic therapy in critically ill patients
Code
3F012211
Duration
01 October 2011 → 30 September 2015
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Medical and health sciences
    • Immunology
    • Laboratory medicine
    • Immunology
    • Laboratory medicine
    • Microbiology
    • Biomarker discovery and evaluation
    • Drug discovery and development
    • Medicinal products
    • Pharmaceutics
    • Pharmacognosy and phytochemistry
    • Pharmacology
    • Pharmacotherapy
    • Toxicology and toxinology
    • Other pharmaceutical sciences
    • Immunology
    • Laboratory medicine
Keywords
Therapeutic Drug Monitoring beta-lactams pharmacokinetic modelling pharmacokinetics Laser Diode Thermal Desorption
 
Project description

The goal of this project is to determine the feasability, safety and efficacy as well as cost-effectiveness of Patient Tailored Antibiotic Therapy (PTABT) in critically ill patients. PTABT is the adaptation of antibiotic therapy to the need of individual patient in order to maximize efficacy and minimize toxicity through measurement of antibiotic concentrations in serum and dose adaptation.