Research Explorer

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Project

Refining cancer cell death and danger signals for the improvement of immunotherapy

Outputs and Outcomes

Publications

Automated antibody dispensing to improve high-parameter flow cytometry throughput and analysis

Victor BosteelsJulie Van DuyseElien RuyssinckKatrien Van Der BorghtLong NguyenJannes GavelSophie JanssensGert Van Isterdael

A1 Journal Article in CYTOMETRY PART A

Decoding immunogenic cell death from a dendritic cell perspective

Sophie JanssensSofie RennenPatrizia Agostinis

A1 Journal Article in IMMUNOLOGICAL REVIEWS

A metabolic gene survey pinpoints fucosylation as a key pathway underlying the suppressive function of regulatory T cells in cancer

Sotiria PiniotiHimal SharmaNina C. FlerinQian YuAmalia TzoumpaSarah Trusso CafarelloElien De BousserNico CallewaertGuillaume OldenhoveSusan SchlennerBernard ThienpontAbhishek D. GargMario Di MatteoMassimiliano Mazzone et al.

A1 Journal Article in CANCER IMMUNOLOGY RESEARCH

Defining solute carrier transporter signatures of murine immune cell subsets

Tania Love AaesJavier BurgoaKodi Ravichandran

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Canonical IRE1 function needed to sustain vigorous natural killer cell proliferation during viral infection

Jessica VettersMary van HeldenClint De NolfSofie RennenEva ClootsEvelien Van De VeldeFarzaneh FayazpourJustine Van MoorleghemManon VanheerswynghelsKarl VergoteLouis BoonEric VivierBart LambrechtSophie Janssens et al.

A1 Journal Article in ISCIENCE

Nuanced role for dendritic cell intrinsic IRE1 RNase in the regulation of antitumor adaptive immunity

Felipe Flores-SantibanezSofie RennenDominique FernandezClint De NolfEvelien Van De VeldeSandra Gaete GonzalezCamila FuentesCarolina MorenoDiego FigueroaAlvaro LladserTakao IwawakiMaria Rosa BonoSophie JanssensFabiola Osorio et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

STE20 kinase TAOK3 regulates type 2 immunity and metabolism in obesity

Bastiaan MaesFarzaneh FayazpourLeen CatrysseGuillaume LornetEvelien Van De VeldeCaroline De WolfSofie De PrijckJustine Van MoorleghemManon VanheerswynghelsKim DeswarteBenedicte DescampsChristian VanhoveBart Van der SchuerenRoman VangoitsenhovenHamida HammadSophie JanssensBart Lambrecht et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

LXR signaling controls homeostatic dendritic cell maturation

Victor BosteelsSandra MaréchalClint De NolfSofie RennenJonathan MaelfaitSimon TavernierJessica VettersEvelien Van De VeldeFarzaneh FayazpourKim DeswarteAlexander LamootJulie Van DuyseLiesbet MartensCedric BosteelsRia RoelandtAnnelies EmmaneelSofie Van GassenLouis BoonGert Van IsterdaelIsabelle GuillasNiels VandammeDoris HöglingerBruno De GeestWilfried Le GoffYvan SaeysKodi RavichandranBart LambrechtSophie Janssens et al.

A1 Journal Article in SCIENCE IMMUNOLOGY

Efficacy of CD40 agonists is mediated by distinct cDC subsets and subverted by suppressive macrophages

Aleksandar MurgaskiMate KissHelena Van DammeDaliya KanchevaIsaure VanmeerbeekJiri KeirsseEva HadadiJan BrughmansSana M. ArnoukAhmed E. I. HamoudaAyla DebraekeleerVictor BosteelsYvon ElkrimLouis BoonSabine HovesNiels VandammeSofie DeschoemaekerSophie JanssensAbhishek D. GargGreetje Vande VeldeMartina SchmittnaegelCarola H. RiesDamya Laoui et al.

A1 Journal Article in CANCER RESEARCH

Clearing your mind : mechanisms of debris clearance after cell death during neural development

Kendra E. LiuMichael H. RaymondKodi RavichandranSarah Kucenas

A1 Journal Article in ANNUAL REVIEW OF NEUROSCIENCE

Cancer cells dying from ferroptosis impede dendritic cell-mediated anti-tumor immunity

Bartosz WiernickiSophia MaschalidiJonathan PinneySandy Adjemian CataniTom Vanden BergheKodi RavichandranPeter Vandenabeele

A1 Journal Article in NATURE COMMUNICATIONS

Drugging the efferocytosis process : concepts and opportunities

Parul MehrotraKodi Ravichandran

A1 Journal Article in NATURE REVIEWS DRUG DISCOVERY

Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes

Sophia MaschalidiParul MehrotraBurcu Nur KeçeliHannah De CleeneKim LecomteRenée Van der CruyssenPauline JanssenJonathan PinneyGeert van LooDirk ElewautAnn MassieEsther HosteKodi Ravichandran et al.

A1 Journal Article in NATURE