Research Explorer

Project

Development and evaluation of particulate formulations for the selective delivery of antigens and immunpotentiators towards dendritic cells.
Code
01P06610
Duration
01 October 2010 → 01 October 2012
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Immunology
    • Immunology
    • Immunology
  • Engineering and technology
    • Process engineering
    • Biomaterials engineering
    • Polymeric materials
    • Biological system engineering
    • Biomaterials engineering
    • Biomechanical engineering
    • Other (bio)medical engineering
    • Environmental engineering and biotechnology
    • Industrial biotechnology
    • Other biotechnology, bio-engineering and biosystem engineering
Keywords
dendritic cells mycobacterium tuberculosis vaccination particulate antigen delivery
 
Project description
 

Developing effective vaccins against insidous pathogens such as HIV, Mycobacterium tuberculosis and HCV represents a major challenge and is likely to require the induction of potent T cell mediated immune responses. In this project we aim to develop a particulate carrier allowing the selective delivery of both antigens and immunpotentiators to dendritic cells in order to promote the induction of potent T cell mediated immune responses.