Code
12TKM112
Duration
01 January 2012 → 31 December 2013
Funding
Federal funding: various
Promotor
Research disciplines
-
Medical and health sciences
- Immunology
- Respiratory medicine
- Immunology
- Microbiology
- Respiratory medicine
- Immunology
- Respiratory medicine
Keywords
kupffer cells
alveolar macrophages
dendritic cells
monocytes
macrophages
asthma
immunoregulation
Project description
Dendritic Cells (DCs) and MFs present antigens to T cells, which differentiate into Effector or Regulatory T cells. Some DCs or MFs may preferentially induce tolerance through Regulatory T cells, while others may preferentially induce Effector T cells. We will study the role of distinct DCs and MFs by restricting antigen-presenting-capacity to one DC or MF subset at a time.