Code
3G032011
Duration
01 January 2011 → 31 December 2014
Funding
Research Foundation - Flanders (FWO)
Promotor
Research disciplines
-
Natural sciences
- Animal biology
- Biochemistry and metabolism
- Evolutionary biology
- General biology
- Genetics
- Systems biology
-
Medical and health sciences
- Medical biochemistry and metabolism
- Medical biochemistry and metabolism
- Social medical sciences
- Medical biochemistry and metabolism
-
Agricultural and food sciences
- Veterinary medicine
Keywords
molecular evolution
model organisms
cell-cell adhesion
Project description
Proposed research aims comprise: 1. analysis of newly sequenced metazoan genomes for novel and conserved cadherin superfamily genes; 2. improved phylogenetic analysis of cadherins across the animal kingdom; 3. structural modeling for selected members; 4. functional assessment by expression analysis for selected interesting cadherin genes; 5. functional assessment of carefully selected cadherin superfamily members by overexpression versus knock down experiments.