01 January 2014 → 31 December 2019
Research Foundation - Flanders (FWO)
- Plant biology
Secretory IgA Feed-based Piglet post weaning diarrhoea Enterotoxigenic Escherichia coli (ETEC) modified glycosylation passive immunisation Human respiratory syncytial virus (HRSV) intranasal
Most pathogens enter through the mucosal surfaces, the entry of which can be blocked by application of antibodies at these surfaces. Our group has produced VHH-IgA based novel antibodies in seeds for application at mucosal surfaces. In this project we aim to study the parameters required for higher efficient production of these antibodies and their efficacy on application at oral and pulmonary mucosa.