Project

Protein engineering as an approach for broadening the substrate scope of industrially relevant enzymes.

Code
01CD00624
Duration
01 April 2024 → 30 September 2024
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Biochemistry and metabolism not elsewhere classified
  • Engineering and technology
    • Biocatalysis and enzyme technology
 
Project description
We propose the addition of mutations into enzymes for industrially relevant reactions to increase their activity and stability . These enzymes include transaminases, hydrolases and lactone esterases. Furthermore, we attempt to evaluate the effect of mutations in the catalytic activity and substrate preference of the enzyme.