The blue economy represents a sustainable approach to economic growth, recognizing the vast potential of the oceans to provide innovative solutions for both environmental sustainability and human health. We explore the intersections of marine biodiscovery and the beneficial effects of living close to the sea, emphasizing the critical role of the oceans in enhancing human well-being. Marine biodiscovery, the exploration of marine organisms for novel compounds and bioactive substances, has emerged as a promising field with profound implications for human health. The oceans are home to an incredible diversity of life forms, many of which possess unique biochemical properties that can be harnessed for pharmaceutical, nutraceutical, and therapeutic applications. Recent advancements in marine biotechnology have led to the discovery of new antibiotics, anti-cancer agents, and anti-inflammatory compounds, showcasing the untapped potential of marine ecosystems in providing innovative health solutions. Additionally, living close to the sea has long been associated with various health benefits, a phenomenon increasingly supported by scientific evidence. Coastal environments offer a unique blend of physical, psychological, and social advantages. Moreover, the sea air is believed to improve respiratory function and boost the immune system. We highlight the synergistic relationship between marine biodiscovery and the health benefits of coastal living within the framework of the blue economy. By fostering sustainable practices and investing in marine research, we can unlock new avenues for health promotion and disease prevention. Furthermore, promoting coastal habitation and ensuring the conservation of marine environments are essential for maximizing these health benefits while safeguarding the ocean's biodiversity. Through the dual lenses of marine biodiscovery and the advantages of coastal living, we can harness the ocean's resources to improve human health, foster sustainable development, and ensure the longevity of our marine ecosystems for future generations.