Research Explorer

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Project

Replication fork protector dependency factors: novel targets for combination treatment and immunomodulation in neuroblastoma (REINFORCE)

Outputs & Impact

Publications & research data ( 10 )

Synergistic inhibition of CHK1 and MUS81 to combat replication stress resistance in high-risk neuroblastoma

Elien HilgertChristophe Van NesteSarah-Lee BekaertFien MartensSuzanne VanhauwaertEllen SandersPeter VerstraelenMartijn RisseeuwEllen M. WesterhoutMark A. Grannetia et al.

A1 Journal Article in SCIENTIFIC REPORTS

MOXD1 is a lineage-specific gene and a tumor suppressor in neuroblastoma

Elina FredlundStina AnderssonElien HilgertEzequiel MonferrerGuadalupe Álvarez-HernánSinan KarakayaSiebe LoontiensJan Willem BekTomas GregorEstelle Lecomte et al.

A1 Journal Article in SCIENCE ADVANCES

NBAtlas : a harmonized single-cell transcriptomic reference atlas of human neuroblastoma tumors

Noah BonineVittorio ZanzaniAnnelies Van HemelrykBavo VannesteChristian ZwickerTinne ThonéSofie RoelandtSarah-Lee BekaertJan KosterIsabelle Janoueix-Lerosey et al.

A1 Journal Article in CELL REPORTS

Characterizing the cell-free transcriptome in a humanized diffuse large B-cell lymphoma patient-derived tumor xenograft model for RNA-based liquid biopsy in a preclinical setting

Philippe DecruyenaereWillem DaneelsAnnelien MorlionKimberly VerniersJasper AnckaertJan TavernierFritz OffnerJo Vandesompele

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Leveraging a self-cleaving peptide for tailored control in proximity labeling proteomics

Louis DelhayeGeorgios MoschonasDaria FijalkowskaAnnick VerheeDelphine De SutterTessa Van de SteeneMargaux De MeyerHanna GrzesikLaura Van MoortelKarolien De Bosscher et al.

A2 Journal Article in CELL REPORTS METHODS

Exploration of neuroblastoma xenograft models for tumor extracellular RNA profiling in murine blood plasma

Jill DeleuHanne Van DroogenbroeckJasper AnckaertAnneleen DecockJilke De WildeKaat DurinckLiselot MusJustine NuytensMuhammad RishfiKathleen Schoofs et al.

A2 Journal Article in EXRNA

Exploring the cell-free total RNA transcriptome in diffuse large B-cell lymphoma and primary mediastinal B-cell lymphoma patients as biomarker source in blood plasma liquid biopsies

Philippe DecruyenaereEdoardo GiuiliKimberly VerniersJasper AnckaertKatrien De GroveMalaïka Van der LindenDries DeerenJo Van DorpeFritz OffnerJo Vandesompele

A1 Journal Article in FRONTIERS IN ONCOLOGY

RNA extraction method impacts quality metrics and sequencing results in formalin-fixed, paraffin-embedded tissue samples

Philippe DecruyenaereKimberly VerniersFranco Alexander Poma SotoJo Van DorpeFritz OffnerJo Vandesompele

A1 Journal Article in LABORATORY INVESTIGATION

Whole transcriptome profiling of liquid biopsies from tumour xenografted mouse models enables specific monitoring of tumour-derived extracellular RNA

Vanessa VermeirssenJill DeleuAnnelien MorlionCeline EveraertJilke De WildeJasper AnckaertKaat DurinckJustine NuytensMuhammad RishfiFranki Speleman et al.

A2 Journal Article in NAR CANCER

RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition

Carolina de Carvalho NunesLisa DepestelLiselot MusKaylee M. KellerLouis DelhayeAmber LouwagieMuhammad RishfiAlex WhaleNeesha KaraSimon R. Andrews et al.

A1 Journal Article in SCIENCE ADVANCES

Activities ( 0 )

Results

Impact narratives ( 0 )

Patents ( 0 )