Project

Interactions in the endoplasmic reticulum which are important in the biogenesis of the dopamine D4 receptor

Duration
01 October 2007 → 30 September 2013
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Biochemistry and metabolism
    • Systems biology
  • Medical and health sciences
    • Medical biochemistry and metabolism
    • Medical biochemistry and metabolism
    • Medical biochemistry and metabolism
Keywords
GPCR chaperones dimerization dopamine
 
Project description

The dopamine D4 receptors is a G protein-coupled receptor (GPCR). Folding of the receptor starts in the endoplasmic reticulum (ER). The influence of different chaperones and proteins involved in the biogenesis of the receptor will be investigated.