Project

Metabolic fingerprinting of the human gut phenotype in health and disease

Duration
01 October 2013 → 30 September 2017
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Agricultural and food sciences
    • Veterinary public health and food safety
Keywords
Metabolic fingerprinting ultrahigh performance liquid chromatography - high resolution Orbitrap mass spectrometry inflammatory bowel disease colorectal cancer prediagnostic screening tool
 
Project description

The main objective of this innovative research is to characterize ‘metabolic phenotypes’, by means of a high resolution full scan Orbitrap mass spectrometer, which will analyse feces, intact biopsies or exfoliated colonocytes. At a later stage of the research these metabolomic fingerprints may serve as a specific statistically founded prediagnostic screening tool for different types of gastrointestinal disorders (inflammatory bowel disease and colorectal cancer).