Research Explorer

Project

Unraveling the role of MYT1L in intellectual disability: an integrated functional genetic approach
Code
3G044615
Duration
01 January 2015 → 31 December 2020
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Genetics
    • Systems biology
  • Social sciences
    • Biological and physiological psychology
    • Cognitive science and intelligent systems
    • Developmental psychology and ageing
  • Medical and health sciences
    • Laboratory medicine
    • Medical systems biology
    • Molecular and cell biology
    • Neurosciences
    • Laboratory medicine
    • Medical systems biology
    • Molecular and cell biology
    • Neurosciences
    • Laboratory medicine
    • Medical systems biology
    • Molecular and cell biology
    • Neurosciences
Keywords
intellectual disability functional analysis transcriptomics proteomics MYT1L
 
Project description
 

MYT1L is a new candidate gene for intellectual disability, due to the embryonic expression restricted to post-mitotic neurons, the association with other neurological disorders and the role in the direct conversion of fibroblasts to functional neurons. By integrating transcriptomics and proteomics we will try to unravel the cellular function of this gene and the pathways wherein it is involved.