Research Explorer

Project

LC-MS in the age of omics: Development of Novel Open-Source Preprocessing Software and Optimized Data Analysis Strategies
Code
01CD02425
Duration
01 September 2025 → 31 December 2025
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Analytical separation and detection techniques
    • Lipidomics
    • Metabolomics
  • Medical and health sciences
    • Development of bioinformatics software, tools and databases
Keywords
mass spectrometry open-source lipidomics bio-informatics Metabolomics liquid chromatography
 
Project description
 The availability of fitfor- purpose analysis and data processing methods for different LC-MS omics (i.e. metabolomics, lipidomics, DNA adductomics) technologies is of paramount importance. In this project, we introduce novel methods to advance LC-MS applications: (1) a dual metabolomics/lipidomics method, (2) development of open-source software for targeted LC-MS preprocessing and (3) optimization of untargeted preprocessing and normalization strategies in DNA adductomics.