Research Explorer

Your browser does not support JavaScript or JavaScript is not enabled. Without JavaScript some functions of this webapplication may be disabled or cause error messages. To enable JavaScript, please consult the manual of your browser or contact your system administrator.

Project

Molecular-genetic mechanisms of extreme adaptation in a polyphagous agricultural pest

Outputs and Outcomes

Publications

Adaptation of an arthropod predator to a challenging environment is associated with a loss of a genome-wide plastic transcriptional response

Sabina Bajda-WybouwNicky WybouwViet Ha NguyenPatrick De ClercqThomas Van Leeuwen

A1 Journal Article in PEST MANAGEMENT SCIENCE

SYNCAS : efficient CRISPR/Cas9 gene-editing in difficult to transform arthropods

Sander De RouckAntonio MocchettiWannes DermauwThomas Van Leeuwen

A1 Journal Article in INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Contrasting roles of cytochrome P450s in amitraz and chlorfenapyr resistance in the crop pest Tetranychus urticae

Marilou VandenholeXueping LuDimitra TsakireliCatherine MermansSander De RouckBerdien De BeerEba Alemayehu SimmaSpiros A. PergantisWim JonckheereJohn VontasThomas Van Leeuwen et al.

A1 Journal Article in INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

A glutamate-gated chloride channel as the mite-specific target-site of dicofol and other diphenylcarbinol acaricides

Marilou VandenholeCatherine MermansBerdien De BeerWenxin XueYilan ZhaoYoshihisa OzoeGenyan LiuWannes DermauwThomas Van Leeuwen

A1 Journal Article in COMMUNICATIONS BIOLOGY

A review of the molecular mechanisms of acaricide resistance in mites and ticks

Sander De RouckEmre InakWannes DermauwThomas Van Leeuwen

A1 Journal Article in INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

The host plant strongly modulates acaricide resistance levels to mitochondrial complex II inhibitors in a multi-resistant field population of Tetranychus urticae

Christine NjiruMarilou VandenholeWim JonckheereNicky WybouwThomas Van Leeuwen

A1 Journal Article in PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Molecular mechanisms of resistance to spirodiclofen and spiromesifen in Tetranychus urticae

Emre InakBerke DemirciMarilou VandenholeGokhan SoylemezogluThomas Van LeeuwenUmut Toprak

A1 Journal Article in CROP PROTECTION

A nuclear receptor HR96-related gene underlies large trans-driven differences in detoxification gene expression in a generalist herbivore

Meiyuan JiMarilou VandenholeBerdien De BeerSander De RouckErnesto Villacis PerezRené FeyereisenRichard M. ClarkThomas Van Leeuwen

A1 Journal Article in NATURE COMMUNICATIONS

Incidence and molecular mechanisms of insecticide resistance in Frankliniella occidentalis, Thrips tabaci and other economically important thrips species

Antonio MocchettiWannes DermauwThomas Van Leeuwen

A1 Journal Article in ENTOMOLOGIA GENERALIS

The complex II resistance mutation H258Y in succinate dehydrogenase subunit B causes fitness penalties associated with mitochondrial respiratory deficiency

Christine NjiruCorinna SaalwaechterKonstantinos MavridisJohn VontasSven GeibelNicky WybouwThomas Van Leeuwen

A1 Journal Article in PEST MANAGEMENT SCIENCE

Incomplete reproductive barriers and genomic differentiation impact the spread of resistance mutations between green- and red-colour morphs of a cosmopolitan mite pest

Wenxin XueJing-Tao SunJohan WittersMarilou VandenholeWannes DermauwSabina Bajda-WybouwEba Alemayehu SimmaNicky WybouwErnesto Villacis PerezThomas Van Leeuwen

A1 Journal Article in MOLECULAR ECOLOGY

Recombinant expression and characterization of GSTd3 from a resistant population of Anopheles arabiensis and comparison of DDTase activity with GSTe2

Xueping LuEba Alemayehu SimmaPieter SpanogheThomas Van LeeuwenWannes Dermauw

A1 Journal Article in PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Intraspecific diversity in the mechanisms underlying abamectin resistance in a cosmopolitan pest

Ernesto Villacis PerezWenxin XueMarilou VandenholeBerdien De BeerWannes DermauwThomas Van Leeuwen

A1 Journal Article in EVOLUTIONARY APPLICATIONS

Increased metabolism in combination with the novel cytochrome b target-site mutation L258F confers cross-resistance between the Qo inhibitors acequinocyl and bifenazate in Tetranychus urticae

Xueping LuMarilou VandenholeDimitra TsakireliSpiros A. PergantisJohn VontasWim JonckheereThomas Van Leeuwen

A1 Journal Article in PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Activity, selection response and molecular mode of action of the isoxazoline afoxolaner in Tetranychus urticae

Catherine MermansWannes DermauwSven GeibelThomas Van Leeuwen

A1 Journal Article in PEST MANAGEMENT SCIENCE

Trans-driven variation in expression is common among detoxification genes in the extreme generalist herbivore Tetranychus urticae

Andre KurlovsBerdien De BeerMeiyuan JiMarilou VandenholeTim De MeyerRené FeyereisenRichard M. ClarkThomas Van Leeuwen

A1 Journal Article in PLOS GENETICS

Interactions with plant defences isolate sympatric populations of an herbivorous mite

Ernesto Villacis PerezJuan Manuel AlbaJulien CotteZeno van LoonJohannes A. J. BreeuwerThomas Van Leeuwen

A1 Journal Article in FRONTIERS IN ECOLOGY AND EVOLUTION

Biochemical and insecticidal effects of plant essential oils on insecticide resistant and susceptible populations of Musca domestica L. point to a potential cross-resistance risk

Ebrahim AhmadiJahangir KhajehaliWim JonckheereThomas Van Leeuwen

A1 Journal Article in PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

The H92R substitution in PSST is a reliable diagnostic biomarker for predicting resistance to mitochondrial electron transport inhibitors of complex I in European populations of Tetranychus urticae

Wenxin XueXueping LuKonstantinos MavridisJohn VontasWim JonckheereThomas Van Leeuwen

A1 Journal Article in PEST MANAGEMENT SCIENCE

Potential of two omnivorous iolinid mites as predators of the tomato russet mite, Aculops lycopersici

Lore VervaetGOKUL PARAPURATHRaf De VisThomas Van LeeuwenPatrick De Clercq

A1 Journal Article in JOURNAL OF PEST SCIENCE

High-resolution genetic mapping combined with transcriptome profiling reveals that both target-site resistance and increased detoxification confer resistance to the pyrethroid bifenthrin in the spider mite Tetranychus urticae

Berdien De BeerMarilou VandenholeChristine NjiruPieter SpanogheWannes DermauwThomas Van Leeuwen

A1 Journal Article in BIOLOGY-BASEL

Intradiol ring cleavage dioxygenases from herbivorous spider mites as a new detoxification enzyme family in animals

Christine NjiruWenxin XueSander De RouckJuan M. AlbaMerijn R. KantMaksymilian ChruszczBartel VanholmeWannes DermauwNicky WybouwThomas Van Leeuwen

A1 Journal Article in BMC BIOLOGY

A H258Y mutation in subunit B of the succinate dehydrogenase complex of the spider mite Tetranychus urticae confers resistance to cyenopyrafen and pyflubumide, but likely reinforces cyflumetofen binding and toxicity

Christine NjiruCorinna SaalwaechterOliver GutbrodSven GeibelNicky WybouwThomas Van Leeuwen

A1 Journal Article in INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Over-expression in cis of the midgut P450 CYP392A16 contributes to abamectin resistance in Tetranychus urticae

Kyriaki Maria PapapostolouMaria RigaGeorge-Rafael SamantsidisEvangelia SkoufaVasileia BalabanidouThomas Van LeeuwenJohn Vontas

A1 Journal Article in INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Structural and functional characterization of beta-cyanoalanine synthase from Tetranychus urticae

Leily DaneshianIsabella RenggliRyan HanawayLesa R. OffermannCaleb R. SchlachterShannon HenryRahul PrakashNicky WybouwWannes DermauwLinda S. ShimizuThomas M. MakrisVojislava GrbicMiodrag GrbicMaksymilian ChruszczRicardo Hernandez ArriazaThomas Van Leeuwen et al.

A1 Journal Article in INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

QTL mapping suggests that both cytochrome P450-mediated detoxification and target-site resistance are involved in fenbutatin oxide resistance in Tetranychus urticae

Berdien De BeerErnesto Villacis PerezMousaalreza KhaglighiCorinna SaalwaechterMarilou VandenholeWim JonckheereIbrahim IsmaeilSven GeibelThomas Van LeeuwenWannes Dermauw

A1 Journal Article in INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Selectivity and molecular stress responses to classical and botanical acaricides in the predatory mite Phytoseiulus persimilis Athias-Henriot (Acari: Phytoseiidae)

Sabina Bajda-WybouwPatrick De ClercqThomas Van Leeuwen

A1 Journal Article in PEST MANAGEMENT SCIENCE

The G126S substitution in mitochondrially encoded cytochrome b does not confer bifenazate resistance in the spider mite Tetranychus urticae

Wenxin XueNicky WybouwThomas Van Leeuwen

A1 Journal Article in EXPERIMENTAL AND APPLIED ACAROLOGY

Adaptive divergence and post-zygotic barriers to gene flow between sympatric populations of a herbivorous mite

Ernesto Villacis PerezSimon SnoeckAndre KurlovsRichard M. ClarkJohannes A. J. BreeuwerThomas Van Leeuwen

A1 Journal Article in COMMUNICATIONS BIOLOGY

High-resolution genetic mapping reveals cis-regulatory and copy number variation in loci associated with cytochrome P450-mediated detoxification in a generalist arthropod pest

Seyedeh Masoumeh FotoukkiaiiNicky WybouwAndre KurlovsDimitra TsakireliSpiros A. PergantisRichard M. ClarkJohn VontasThomas Van Leeuwen

A1 Journal Article in PLOS GENETICS

Reduced proinsecticide activation by cytochrome P450 confers coumaphos resistance in the major bee parasite Varroa destructor

Spyridon VlogiannitisKonstantinos MavridisWannes DermauwSimon SnoeckEvangelia KatsavouEvangelia MorouPaschalis HarizanisLuc SweversJanet HemingwayRené FeyereisenThomas Van LeeuwenJohn Vontas et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Untangling a Gordian knot : the role of a GluCl3 I321T mutation in abamectin resistance in Tetranychus urticae

Wenxin XueCatherine MermansKyriaki-Maria PapapostolouMantha LamprousiIason-Konstantinos ChristouEmre InakVassilis DourisJohn VontasWannes DermauwThomas Van Leeuwen

A1 Journal Article in PEST MANAGEMENT SCIENCE

Is the emerging mite pest Aculops lycopersici controllable? Global and genome-based insights in its biology and management

Lore VervaetRaf De VisPatrick De ClercqThomas Van Leeuwen

A1 Journal Article in PEST MANAGEMENT SCIENCE

Short term transcriptional responses of P450s to phytochemicals in insects and mites

Marilou VandenholeWannes DermauwThomas Van Leeuwen

A1 Journal Article in CURRENT OPINION IN INSECT SCIENCE

Identification and characterization of striking multiple-insecticide resistance in a Tetranychus urticae field population from Greece

Kyriaki Maria PapapostolouMaria RigaJason CharamisEvangelia SkoufaVassilis SouchlasAris IliasWannes DermauwPanagiotis IoannidisThomas Van LeeuwenJohn Vontas

A1 Journal Article in PEST MANAGEMENT SCIENCE

Diversity and evolution of the P450 family in arthropods

Wannes DermauwThomas Van LeeuwenRené Feyereisen

A1 Journal Article in INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Genome streamlining in a minute herbivore that manipulates its host plant

Robert GreenhalghWannes DermauwJoris J. GlasStephane RombautsNicky WybouwJainy ThomasJuan M. AlbaEllen J. PrithamSaioa LegarreaRené FeyereisenYves Van de PeerThomas Van LeeuwenRichard M. ClarkMerijn R. Kant et al.

A1 Journal Article in ELIFE

Significance and interpretation of molecular diagnostics for insecticide resistance management of agricultural pests

Thomas Van LeeuwenWannes DermauwKonstantinos MavridisJohn Vontas

A1 Journal Article in CURRENT OPINION IN INSECT SCIENCE

Improving the compatibility of pesticides and predatory mites : recent findings on physiological and ecological selectivity

Carlo DusoThomas Van LeeuwenAlberto Pozzebon

A1 Journal Article in CURRENT OPINION IN INSECT SCIENCE

Geographical distribution and molecular insights into abamectin and milbemectin cross-resistance in European field populations of Tetranychus urticae

Wenxin XueSimon SnoeckChristine NjiruEmre InakWannes DermauwThomas Van Leeuwen

A1 Journal Article in PEST MANAGEMENT SCIENCE

Resistance risk assessment of the novel complex II inhibitor pyflubumide in the polyphagous pest Tetranychus urticae

Seyedeh Masoumeh FotoukkiaiiCatherine MermansNicky WybouwThomas Van Leeuwen

A1 Journal Article in JOURNAL OF PEST SCIENCE

Metabolic mechanisms of resistance to spirodiclofen and spiromesifen in Iranian populations of Panonychus ulmi

Fahimeh BadieiniaJahangir KhajehaliRalf NauenWannes DermauwThomas Van Leeuwen

A1 Journal Article in CROP PROTECTION

Targeted mutagenesis using CRISPR-Cas9 in the chelicerate herbivore Tetranychus urticae

Wannes DermauwWim JonckheereMaria RigaIoannis LivadarasJohn VontasThomas Van Leeuwen

A1 Journal Article in INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Molecular and genetic analysis of resistance to METI-I acaricides in Iranian populations of the citrus red mite Panonychus citri

Elaheh Shafiei AlavijehJahangir KhajehaliSimon SnoeckRafaela PanteleriMohammad GhadamyariWim JonckheereSabina Bajda-WybouwCorinna SaalwaechterSven GeibelVassilis DourisJohn VontasThomas Van LeeuwenWannes Dermauw et al.

A1 Journal Article in PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Identification and geographical distribution of pyrethroid resistance mutations in the poultry red mite Dermanyssus gallinae

Evangelia KatsavouSpyros VlogiannitisEleanor Karp‐TathamDamer P BlakeAris IliasChristina StrubeIlias KioulosWannes DermauwThomas Van LeeuwenJohn Vontas

A1 Journal Article in PEST MANAGEMENT SCIENCE

Identification and characterization of new mutations in mitochondrial cytochrome b that confer resistance to bifenazate and acequinocyl in the spider mite Tetranychus urticae

Seyedeh Masoumeh FotoukkiaiiZoë TanWenxin XueNicky WybouwThomas Van Leeuwen

A1 Journal Article in PEST MANAGEMENT SCIENCE

Overexpression of an alternative allele of carboxyl/choline esterase 4 (CCE04) of Tetranychus urticae is associated with high levels of resistance to the keto‐enol acaricide spirodiclofen

Peng WeiPeter DemaeghtKristof De SchutterLinda GrigorakiVassiliki LabropoulouMaria RigaJohn VontasRalf NauenWannes DermauwThomas Van Leeuwen

A1 Journal Article in PEST MANAGEMENT SCIENCE

Characterization of abamectin resistance in Iranian populations of European red mite, Panonychus ulmi Koch (Acari: Tetranychidae)

Fariborz RameshgarJahangir KhajehaliRalf NauenWannes DermauwThomas Van Leeuwen

A1 Journal Article in CROP PROTECTION

Trait mapping in diverse arthropods by bulked segregant analysis

Andre KurlovsSimon SnoeckOlivia KosterlitzThomas Van LeeuwenRichard M Clark

A1 Journal Article in CURRENT OPINION IN INSECT SCIENCE

Resistance incidence and presence of resistance mutations in populations of Tetranychus urticae from vegetable crops in Turkey

Emre İnakYasin Nazım AlpkentSultan ÇobanoğluWannes DermauwThomas Van Leeuwen

A1 Journal Article in EXPERIMENTAL AND APPLIED ACAROLOGY

Convergent evolution of cytochrome P450s underlies independent origins of keto-carotenoid pigmentation in animals

Nicky WybouwAndre KurlovsRobert GreenhalghAstrid BryonOlivia KosterlitzYuki ManabeMasahiro OsakabeJohn VontasRichard M ClarkThomas Van Leeuwen

A1 Journal Article in PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Point mutations in the voltage-gated sodium channel gene associated with pyrethroid resistance in Iranian populations of the European red mite Panonychus ulmi

Fariborz RameshgarJahangir KhajehaliRalf NauenSabina Bajda-WybouwWim JonckheereWannes DermauwThomas Van Leeuwen

A1 Journal Article in PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Structural and functional characterization of an intradiol ring-cleavage dioxygenase from the polyphagous spider mite herbivore Tetranychus urticae Koch

Caleb R SchlachterLeily DaneshianJose AmayaVincent KlapperNicky WybouwTomasz BorowskiThomas Van LeeuwenVojislava GrbicMiodrag GrbicThomas M MakrisMaksymilian Chruszcz et al.

A1 Journal Article in INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

High-resolution QTL mapping in Tetranychus urticae reveals acaricide-specific responses and common target-site resistance after selection by different METI-I acaricides

Simon SnoeckAndre KurlovsSabina Bajda-WybouwRené FeyereisenRobert GreenhalghErnesto Villacis-PerezOlivia KosterlitzWannes DermauwRichard M ClarkThomas Van Leeuwen

A1 Journal Article in INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Long-term population studies uncover the genome structure and genetic basis of xenobiotic and host plant adaptation in the herbivore Tetranychus urticae

Nicky WybouwOlivia KosterlitzAndre KurlovsSabina Bajda-WybouwRobert GreenhalghSimon SnoeckHuyen BuiAstrid BryonWannes DermauwThomas Van LeeuwenRichard M Clark et al.

A1 Journal Article in GENETICS

Substrate specificity and promiscuity of horizontally transferred UDP-glycosyltransferases in the generalist herbivore Tetranychus urticae

Simon SnoeckNena PavlidiDimitra PipiniJohn VontasWannes DermauwThomas Van Leeuwen

A1 Journal Article in INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY