Research Explorer

Project

Identification of therapeutically relevant organ-specific target genes of the Wnt pathway
Code
365O2310
Duration
01 January 2011 → 31 December 2012
Funding
Funding by bilateral agreement (private and foundations)
Research disciplines
  • Natural sciences
    • Genetics
  • Medical and health sciences
    • Gastro-enterology and hepatology
    • Gynaecology and obstetrics
    • Molecular and cell biology
    • Morphological sciences
    • Oncology
    • Gastro-enterology and hepatology
    • Gynaecology and obstetrics
    • Molecular and cell biology
    • Morphological sciences
    • Oncology
    • Gastro-enterology and hepatology
    • Gynaecology and obstetrics
    • Molecular and cell biology
    • Morphological sciences
    • Oncology
Keywords
development cancer Wnt signaling Xenopus
 
Project description
 

A microarry screen for primary target genes of he Wnt/b-catenin pathway was conducted in several organs of the model organismWenopus. We identified several putative target genes that will be functionally analyzed in this project. We will focus on genes involved in human colon cancer. Several mouse tumor models will be used in this project.