Research Explorer

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Project

Development and evaluation of leptin receptor antagonist as a therapeutisch strategy for multiple sclerosis

Outputs and Outcomes

Code

31519408

Duration

01 January 2008 → 31 December 2010

Funding

Research Foundation - Flanders (FWO)

Promotor

Jan Tavernier

Research disciplines

Medical and health sciences
- Endocrinology and metabolic diseases
- Endocrinology and metabolic diseases
- Endocrinology and metabolic diseases

Keywords

evaluation Multiple Sclerosis (MS)

Project description

The weight regulating hormone leptin plays a crucial role in the onset and progression of a series of T-cell mediated auto-immune diseases, like multiple sclerosis (MS). The aim of the project is to design and evaluate nanobodies, a relatively new technique based on the use of camel antibodies, directed against the leptin receptor in a relapsing-remitting MS model.

English

Dutch

English

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