Nanochemical Cellular Imaging using Synchrotron Radiation X-ray Spectroscopy

01 October 2010 → 01 October 2012
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Classical physics
    • Elementary particle and high energy physics
    • Other physical sciences
    • Analytical chemistry
    • Biochemistry and metabolism
  • Medical and health sciences
    • Medical biochemistry and metabolism
    • Medical biochemistry and metabolism
    • Pharmaceutical analysis and quality assurance
    • Medical biochemistry and metabolism
XRF NETs synchrotron
Project description

This project aims the further development and applications of XRF nanotomgraphy and confocal nanoanalysis as 2D/3D quantitative methods for single-cell trace-level elemental imaging in biological model systems under cryogenic conditions. The application of the developed nannochemical imaging techniques will be demonstrated on Neutrophil Extracellular Traps (NETs), which will contribute to the understanding on how neutrophils can defeat fungal pathogens.