Acronym
Ex ovo omnia
Code
01G03018
Duration
01 January 2018 → 31 December 2022
Funding
Regional and community funding: Special Research Fund
Promotor-spokesperson
Research disciplines
-
Natural sciences
- Animal biology
- Genetics
-
Medical and health sciences
- Gynaecology and obstetrics
- Molecular and cell biology
- Morphological sciences
- Gynaecology and obstetrics
- Molecular and cell biology
- Morphological sciences
- Gynaecology and obstetrics
- Molecular and cell biology
- Morphological sciences
-
Agricultural and food sciences
- Veterinary medicine
- Other veterinary sciences
- Other agricultural, veterinary and food sciences
Keywords
Oocyte
stem cell
assisted reproduction
fertility preservation
female subfertility
Project description
Female infertility is often associated with inferior oocyte quality. To cure this problem we will develop a bovine and human 3D model for final in vitro oocyte maturation. Moreover, mature oocytes will be generated after oogenesis
in vitro starting from human embryonic stem cells. Epigenetic and chromosomal stability and functionality will be evaluated in mature oocytes and embryos to guarantee safety of this novel therapy.