Project

Induction of safe but potent anti-tumour responses via lymph node focused nanoparticle-mediated immune activation

Duration
01 October 2016 → 30 September 2019
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Engineering and technology
    • Chemical product design and formulation
    • Biomaterials engineering
Keywords
cancer nanotechnology dendritic cells
 
Project description

The aim of this project is to develop a nanoparticle platform that efficiently delivers tumor assoicated antigens and immuno-modulatory stimuli to dendritic cells in the draining lymph nodes. For this purpose we will combine polymer chemistry, self-assembly and bioconjugation with immunology and oncology. The ultimate goal is to obtain a potent but safe anti-cancer vaccination strategy.