Project

Long noncoding RNAs in cancer: deciphering the functional role of the dark matter of the human cancer genome

Code
01GB2316
Duration
01 January 2016 → 31 October 2021
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Scientific computing
    • Bioinformatics and computational biology
  • Medical and health sciences
    • Bioinformatics and computational biology
    • Morphological sciences
    • Oncology
    • Bioinformatics and computational biology
    • Morphological sciences
    • Oncology
    • Public health care
    • Public health services
    • Bioinformatics and computational biology
    • Morphological sciences
    • Oncology
  • Engineering and technology
    • Scientific computing
Keywords
biomarker cancer long non-coding RNAs therapy
 
Project description

The human genome is pervasively transcribed and produces thousands of yet unexplored long non-coding RNAs (lncRNAs). With this project, we aim to uncover novel lncRNAs with therapeutic or biomarker potential in cancer. This is achieved through an elaborate discovery and validation workflow, supported by novel laboratory technologies and data analysis strategies that will be implemented during the course of this project.