Research Explorer

Project

LNP-DECODE: Deciphering the adjuvants activity of lipid nanoparticle-based mRNA vaccines in primary dendritic cells
Code
01G01524
Duration
01 January 2024 → 31 December 2027
Funding
Regional and community funding: Special Research Fund
Promotor-spokesperson
Research disciplines
  • Natural sciences
    • Intracellular compartments and transport
  • Medical and health sciences
    • Adaptive immunology
    • Innate immunity
    • Biopharmaceuticals
    • Vaccines
Keywords
mRNA vaccines dendritic cells immune response
 
Project description
 

This project aims to put UGent at the forefront of mRNA-vaccine research by providing in-depth insights in the adjuvant properties of LNP-based mRNA-vaccines. To this end, we will join the expertise of 3 teams working on dendritic cell biology, nucleic acid sensors and lipid nanoparticles respectively.This consortium will form the basis for the development of vaccines against autoimmune diseases.