Synthesis of phosphonylated azadienes as building blocks for azaheterocyclic phosphonates

01 October 2011 → 30 September 2015
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Organic chemistry
    • Other chemical sciences
  • Engineering and technology
    • Chemical product design and formulation
  • Agricultural and food sciences
    • Agricultural plant production
phosphonoazadienes pyridylposphonates azaheterocylic rings
Project description

The aim of this project is the synthesis of innovative phosphonylated azadienes, i.e. 4-phosphono-2-aza-1,3-dienes, as precursors for phosphonylated azaheterocyclic three-, four-, five- and six-membered rings. The reactivity of these 4-phosphono-2-aza-1,3-dienes will be studied in depth using carbenes and different types of nucleophiles. Further, a direct synthesis of 3-pyridylphosphonates is envisaged.