Research Explorer

Your browser does not support JavaScript or JavaScript is not enabled. Without JavaScript some functions of this webapplication may be disabled or cause error messages. To enable JavaScript, please consult the manual of your browser or contact your system administrator.

Project

Immunological memory of the macrophage niche (MacNicheMemo)

Outputs & Impact

Publications & research data ( 14 )

SPArrOW : a flexible, interactive and scalable pipeline for spatial transcriptomics analysis

Lotte PollarisBavo VannesteBenjamin RombautArne DefauwFrank VernaillenJulien MortierWout VanhendenLiesbet MartensTinne ThonéJean-François Hastir et al.

Infection history imprints prolonged changes to the epigenome, transcriptome and function of Kupffer cells

Mohamed Amer MusratiBenoit StijlemansAbdulkader AzouzDaliya KanchevaSarah MesbahiEva HadadiEls LebeggeLeen AliKaren De VlaminckIsabelle Scheyltjens et al.

A1 Journal Article in JOURNAL OF HEPATOLOGY

Tissue niche occupancy determines the contribution of fetal- versus bone-marrow-derived macrophages to IgG effector functions

Miriam WöhnerSarah BrechtelsbauerNiklas FriedrichChristof VorsatzJohanna BulangChunguang LiangLena SchorrAlain BeschinMartin GuilliamsJeffrey Ravetch et al.

A1 Journal Article in CELL REPORTS

Time and place : mapping human prenatal macrophages across tissues

Camille WagnerMartin Guilliams

Editorial material

Transient Kupffer cell depletion and subsequent replacement by infiltrating monocyte-derived cells does not alter the induction or progression of hepatocellular carcinoma

Bart VanderborghtKevin De MuynckEva GijbelsSander LefereCharlotte ScottMartin GuilliamsAlain BeschinMathieu VinkenXavier VerhelstAnja Geerts et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Macrophage superclusters to the rescue

Pieter LouweMartin Guilliams

Editorial material

The role of recruitment versus training in influenza-induced lasting changes to alveolar macrophage function

Chrysante S. IliakisJustina KulikauskaiteHelena Catharine AegerterFengqi LiFederica PiattiniClaudia V. JakubzickMartin GuilliamsManfred KopfAndreas Wack

Editorial material

Kupffer cells contested as early drivers in the pathogenesis of primary sclerosing cholangitis

Kevin De MuynckBart VanderborghtFederico Francesco De PontiEva GijbelsSophie Van WeldenMartin GuilliamsCharlotte ScottAlain BeschinMathieu VinkenSander Lefere et al.

A1 Journal Article in AMERICAN JOURNAL OF PATHOLOGY

Single-cell RNA and protein profiling of immune cells from the mouse brain and its border tissues

Isabelle ScheyltjensHannah Van HoveKaren De VlaminckDaliya KanchevaJonathan BastosMonica Vara-PerezAna Rita Pombo AntunesLiesbet MartensCharlotte ScottJo Van Ginderachter et al.

A1 Journal Article in NATURE PROTOCOLS

Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment

Cedric BosteelsKarel Van DammeElisabeth De LeeuwJozefien DeclercqBastiaan MaesVictor BosteelsLevi HosteLeslie NaesensNincy DebeufJulie Deckers et al.

A1 Journal Article in CELL REPORTS MEDICINE

Liver macrophages in health and disease

Martin GuilliamsCharlotte Scott

A1 Journal Article in IMMUNITY

Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches

Martin GuilliamsJohnny BonnardelBirthe HaestBart VanderborghtCamille WagnerAnneleen RemmerieAnna BujkoLiesbet MartensTinne ThonéRobin Browaeys et al.

A1 Journal Article in CELL

COMMD10 is critical for Kupffer cell survival and controls Ly6C(hi) monocyte differentiation and inflammation in the injured liver

Keren CohenOdelia MouhadebShani Ben ShlomoMarva LangerAnat NeumannNoam ErezItay MoshkovitsRotem PeletDaniel J. KedarEli Brazowski et al.

A1 Journal Article in CELL REPORTS

Does tissue imprinting restrict macrophage plasticity?

Martin GuilliamsFreya Svedberg

A1 Journal Article in NATURE IMMUNOLOGY

Activities ( 0 )

Results

Impact narratives ( 0 )

Patents ( 0 )