A discrete multiscale biophysical model of cardiac tissue and its application to study cardiac arrhythmias due to tissue anisotropy.

01 December 2015 → 30 September 2020
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Analysis
    • Applied mathematics in specific fields
    • Computer architecture and networks
    • Distributed computing
    • Information sciences
    • Information systems
    • Programming languages
    • Scientific computing
    • Theoretical computer science
    • Visual computing
    • Other information and computing sciences
  • Medical and health sciences
    • Biophysics
    • Biophysics
    • Biophysics
biophysics cardiac modeling anisotropic propagation cardiac arrhythmias anatomical model of the heart tissue development
Project description

Cardiac arrhythmias is a major cause of death in the industrialised world. They occur due to abnormal wave propagation. The most important factor affecting wave propagation is anisotropy of cardiac tissue. We will perform a combined in silico (at UGent) and experimental (at MIPT) study to reveal underlying biophysical mechanisms of the anisotropy and its effects on onset of arrhythmias.