Research Explorer

Project

Development of tissue engineeredaortic hearth valves
Code
01E03108
Duration
01 October 2008 → 30 September 2014
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Medical and health sciences
    • Cardiac and vascular medicine
    • Cardiac and vascular medicine
    • Biomarker discovery and evaluation
    • Drug discovery and development
    • Medicinal products
    • Pharmaceutics
    • Pharmacognosy and phytochemistry
    • Pharmacology
    • Pharmacotherapy
    • Toxicology and toxinology
    • Other pharmaceutical sciences
    • Cardiac and vascular medicine
  • Engineering and technology
    • Process engineering
    • Polymeric materials
Keywords
tissue engineering polymers growht factors
 
Project description
 

The goal of this project is to achieve repopulation of biolocial aortic hearth matrices in order to obrain a vial tissue-engineerded construct that could serve as prototype for a tissue engineered heart valve. Four main sub objectives can be defined: (1) matrix optimalization, (2) Incorporation of growth factors in the biological matrix (3) Repopulation of the growht factor loaded matrices, '4) In vivo evaluation of tissue engineerded heart valves.