Project

Biofarmaceutical proteins: glyco-engineering technology to produce enhanced, homogene glycoforms

Duration
01 October 2010 → 05 January 2016
Funding
Regional and community funding: IWT/VLAIO
Research disciplines
  • Natural sciences
    • Biochemistry and metabolism
    • Systems biology
  • Medical and health sciences
    • Immunology
    • Medical biochemistry and metabolism
    • Immunology
    • Medical biochemistry and metabolism
    • Immunology
    • Medical biochemistry and metabolism
Keywords
biotechnology recombinant proteins glycobiology
 
Project description

Glycoengineering of HEK293 cells to produce recombinant proteins with minimal glycosylation. This will be done by expressing endoT, an endoglycosydase, in these HEK293 cells. The engineering wil be tested by two example proteins: etanercept and hemagglutinin