Project

Modelling of the drying process of porous granules in pharmaceutical continuous operation: a mechanistic approach

Duration
01 October 2011 → 30 September 2015
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Applied mathematics in specific fields
    • Computer architecture and networks
    • Distributed computing
    • Information sciences
    • Information systems
    • Programming languages
    • Scientific computing
    • Theoretical computer science
    • Visual computing
    • Other information and computing sciences
  • Medical and health sciences
    • Biomarker discovery and evaluation
    • Drug discovery and development
    • Medicinal products
    • Pharmaceutics
    • Pharmacognosy and phytochemistry
    • Pharmacology
    • Pharmacotherapy
    • Toxicology and toxinology
    • Other pharmaceutical sciences
Keywords
PBM production of tablets fluidized bed dryer CFD continuous production pharmaceutical processes mechanistic modelling
 
Project description

Mechanistic models of pharmaceutical processes are required to predict and control the continuous production of tablets based on real-time measurements and adjustment of significant process variables. The development of these models will adopt a step-wise approach. In this project the focus will be the drying process of wer granules in a fluidized bed dryer.