The issue of climate change is inevitable in today's mind-set. Beside the socio-economic consequences of global warming, there is a growing awareness of the impact of climate change in the building sector. Many studies focus on the heating and cooling demand of buildings. There are only a handful of studies on premature failure of building envelope enclosures due to moisture degradation with regards to climate change. Especially, research based on hygrothermal modelling remains rather scarce. Besides, there is currently no state-of-the-art approach to implement information on climate change in HAM simulations. To answer to this gap in the field of research, this project aims to develop a methodology to select representative climate conditions, and preliminary guidelines to account for climate change in HAM simulations for research institutions and the building industry.