The working mechanism of a new class of adjuvant, the Layered Double Hydroxide (LDH) family.

01 October 2012 → 15 November 2015
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Medical and health sciences
    • Immunology
    • Immunology
    • Immunology
layered double hydroxide adjuvant vaccination cellular and molecular working mechanism
Project description

This interdisciplinary project combines key aspects of chemistry and immunology to predict which members of a new class of adjuvants, the Layered double hydroxide family (LDH), induce a better cellular and/or humoral immune response than the common used adjuvant alum. Besides, we will unravel their cellular and molecular mechanism of action and their applicability in an influenza infection model.