Code
3G0C1514
Duration
01 January 2014 → 31 December 2019
Funding
Research Foundation - Flanders (FWO)
Promotor
Research disciplines
-
Engineering and technology
- Biocatalysis and enzyme technology
- Industrial biotechnology diagnostics
Keywords
bimodal targetting
Candida albicans
erg11
P450
Project description
In this project we aim to understand the genetics and molecular biology of bimodal targeting of proteins in yeast. Whereas this mechanism has been described in mammalian cells, this is the first time that it has been found in yeasts. Bimodal targeting furthermore takes part in the acquisition of drug resistance in pathogenic yeasts, an aspect which is also addressed.