Research Explorer

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Project

Immunopeptidomics-based Development of Next-Generation Bacterial mRNA Vaccines

Outputs and Outcomes

Publications

Paneth cell TNF signaling induces gut bacterial translocation and sepsis

Charlotte WallaeysNatalia Garcia GonzalezSteven TimmermansJolien VandewalleTineke VanderhaeghenSomara De BeulHester DufoorMelanie EggermontElise MoensVictor BosteelsRiet De RyckeFabien Henri TheryFrancis ImpensSerge VerbanckStefan LienenklausSophie JanssensRichard S. BlumbergTakao IwawakiClaude Libert et al.

A1 Journal Article in CELL HOST & MICROBE

Immunopeptidomics mapping of Listeria monocytogenes T cell epitopes in mice

Adillah GulLecia L. PewePatrick WillemsRupert MayerFabien Henri TheryCaroline AsselmanIlke AernoutRein VerbekeDenzel EggermontLaura Van MoortelEllen UptonYifeng ZhangKatie BoucherLaia Miret CasalsHans DemolStefaan De SmedtIne LentackerLilliana RadoshevichJohn T. HartyFrancis Impens et al.

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Alpha-galactosylceramide improves the potency of mRNA LNP vaccines against cancer and intracellular bacteria

Sofie MeulewaeterIlke AernoutJoke DeprezYanou EngelenMargo De VelderLorenzo FranceschiniKarine BreckpotSerge Van CalenberghCaroline AsselmanKatie BoucherFrancis ImpensStefaan De SmedtRein VerbekeIne Lentacker et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

MS²Rescore 3.0 is a modular, flexible, and user-friendly platform to boost peptide identifications, as showcased with MS Amanda 3.0

Louise M. BuurArthur DeclercqMarina StroblRobbin BouwmeesterSven DegroeveLennart MartensViktoria DorferRalf Gabriels

A1 Journal Article in JOURNAL OF PROTEOME RESEARCH

Considerations on the design of lipid-based mRNA vaccines against cancer

Sofie MeulewaeterYao ZhangAbishek WadhwaKevin FoxIne LentackerKenneth W. HarderPieter R. CullisStefaan De SmedtMiffy H.Y. ChengRein Verbeke

A1 Journal Article in JOURNAL OF MOLECULAR BIOLOGY

Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine

Thomas ErtveldtSofie MeulewaeterYannick De VlaeminckOscar OlarteKatrijn BroosSerge Van CalenberghStephanie BourgeoisJoke DeprezYves HeremansCleo GoyvaertsWillem StaelsStefaan De SmedtHeleen DewitteNick DevoogdtMarleen KeyaertsRein VerbekeKurt BarbéIne LentackerKarine Breckpot et al.

A1 Journal Article in THERANOSTICS

Continuous freeze-drying of messenger RNA lipid nanoparticles enables storage at higher temperatures

Sofie MeulewaeterGust NuyttenMiffy H.Y. ChengStefaan De SmedtPieter R. CullisThomas De BeerIne LentackerRein Verbeke

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE